About Metabolic Syndrome

What is the Metabolic Syndrome?

The metabolic syndrome (MetS) is a cluster of interrelated risk factors that have been found to be associated with future cardiovascular disease and type 2 diabetes.

How is the Metabolic Syndrome Defined?

One commonly used criterion is the ATP-III, where an adult is classified as having MetS if he/she has 3 or more of the following features (1):

  • Waist circumference:
    • >102 cm in men
    • >88 cm in women
  • Triglycerides> 150 mg/dL
  • HDL-C:
    • < 40 mg/dL in men
    • < 50 mg/dL in women
  • Blood pressure> 130/85 mm Hg
  • Glucose > 100 mg/dL, or diagnosed diabetes

However, numerous proposed criteria exist, and even more definitions have been proposed for use in children.


  1. Grundy SM, Cleeman JI, Daniels SR, Donato KA, Eckel RH, Franklin BA, Gordon DJ, Krauss RM, Savage PJ, Smith SC Jr, Spertus JA, Costa F; American Heart Association; National Heart, Lung, and Blood Institute. Diagnosis and management of the metabolic syndrome: an American Heart Association/National Heart, Lung, and Blood Institute Scientific Statement [published corrections appear in 2005;112:e297 and Circulation.2005;112:e298]. Circulation. 2005; 112: 2735–2752