About Metabolic Syndrome

What is the Metabolic Syndrome?

The metabolic syndrome (MetS) is a cluster of interrelated risk factors that have been found to be associated with future cardiovascular disease and type 2 diabetes.

How is the Metabolic Syndrome Defined?

One commonly used criterion is the ATP-III, where an adult is classified as having MetS if he/she has 3 or more of the following features (1):

  • Waist circumference:
    • >102 cm in men
    • >88 cm in women
  • Triglycerides> 150 mg/dL
  • HDL-C:
    • < 40 mg/dL in men
    • < 50 mg/dL in women
  • Blood pressure> 130/85 mm Hg
  • Glucose > 100 mg/dL, or diagnosed diabetes

However, numerous proposed criteria exist, and even more definitions have been proposed for use in children.

References:

  1. Grundy SM, Cleeman JI, Daniels SR, Donato KA, Eckel RH, Franklin BA, Gordon DJ, Krauss RM, Savage PJ, Smith SC Jr, Spertus JA, Costa F; American Heart Association; National Heart, Lung, and Blood Institute. Diagnosis and management of the metabolic syndrome: an American Heart Association/National Heart, Lung, and Blood Institute Scientific Statement [published corrections appear in 2005;112:e297 and Circulation.2005;112:e298]. Circulation. 2005; 112: 2735–2752